This course introduces and provides an overview of the instruments that are commonly found in the biomedical, life science, and biophysical research fields. Students will learn about (1) which types of instruments exist, (2) the science behind the measurements, (3) the nuts & bolts configuration of the instruments, and (4) the types of biomedical systems they can best interrogate. The course utilizes primary scientific literature sources and includes observation and inspection of select instruments. The goal of the course is to familiarize students with the interdisciplinary tools that they will need to be successful in a career in biomedical research.